• Ensure compliance with the international ethical requirements • Approval of information and communication on HIV vaccine trials in Zimbabwe. • Advise on populations suitable for clinical evaluation of HIV/AIDS vaccines. • Build national consensus on a comprehensive, well-coordinated, long-term strategy for developing and evaluating safe, efficacious and affordable preventive, therapeutic and perinatal HIV/AIDS vaccines. • Develop and provide a framework for regulatory approval of research trials, manufacture and licensing of HIV/AIDS vaccines and vaccine products in collaboration with relevant departments. • Provide guidelines for scientific and ethical review of protocols for HIV/AIDS vaccine trials. • Interact with other ministries and national research agencies; • Interact with international agencies and the pharmaceutical industry. • Provide guidelines for monitoring the conduct of HIV/AIDS vaccine trials according to scientifically and ethically acceptable standards. • Suggest ways and means of ensuring availability, accessibility and affordability of efficacious HIV/AIDS vaccines • Suggest ways and means of building local infrastructure and the transfer of knowledge and technology on HIV and AIDS vaccines. 17