FOREWORD ……..….The purpose of this document is to provide guidance to government and non governmental sectors and scientific groups in Zimbabwe working with international regional and national stakeholders and communities in the development and evaluation of candidate vaccines relevant to Zimbabwe. The guidelines are to be used by authorities responsible for the approval, coordination and supervision of candidate vaccine tries in the country. It provides useful resources to members of scientific and review committees as well as national medicines regulatory and biosafety authorities in regulating HIV vaccine trials in Zimbabwe. 2

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