Virological and immunological studies and the development and production of supplies and vaccines Specific projects in the different areas involved should be formulated, not only for developing clinical trials but also particularly for the transfer of technology, with local research and production of supplies and of the vaccine candidates themselves. The position of the MINISTRY OF HEALTH is that: 1. All efforts should be combined to prevent the greater dissemination of HIV infection, to continue prevention activities, to propagate appeals for solidarity and nondiscrimination, to provide treatment against the virus and opportunistic infections and to carry out research on new drugs and vaccines; 2. In international projects, all researchers involved must collaborate in all steps of the trials, from the planning of the protocols to the utilization of the results obtained; 3. The different Phase I/II trials conducted in the countries of origin may be repeated in Zimbabwe whenever deemed convenient. This is justified by possible differences in immunological responses and side effects due to factors such as nutritional status, different viral strains, and presence of other infections and/or genetic differences in the different populations. Repeated or parallel Phase I/II studies will also contribute to staff training and institutional strengthening; 4. Research projects must include training at all levels, not only related to the specific research. This includes support to infrastructure and improvement of research conditions; 34